Human IL-7
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Interleukin-7 (IL-7) is a key cytokine essential for immune system development and maintenance. Produced primarily by stromal cells in the bone marrow and thymus, it supports T and B cell survival, growth, and maturation. IL-7 binds to its receptor complex (IL-7Rα and γc), activating signaling pathways like JAK/STAT to sustain a diverse T cell repertoire crucial for adaptive immunity.
Recombinant human IL-7 is regularly used in vitro to study T cell biology, immune reconstitution, and drug discovery. It helps analyze signal transduction, gene expression, and cell proliferation, aiding in the development of therapies for immunodeficiency and immune-related disorders.
| Cat. No. | RC0007 |
|---|---|
| Purity | >95% in SDS-PAGE followed by coomassie staining |
| Endotoxin Level | <0.01 EU/µg (LAL Assay) |
| Source | Purified from the culture supernatant of HEK 293 cells genetically engineered to express human IL-7 protein with a C-terminal His tag. |
| Accession # | AAA59156 |
| Applications/Intended Use | Research Use Only: This product is intended for laboratory research use only. It is not intended for any animal or human therapeutic use, any human or animal consumption, or any diagnostic use. |
| Molecular Mass | Predicted mass (17 kDa), appears 20-25 kDa due to glycosylation |
| Formulation | Lyophilized from a 0.1 μm filtered solution in PBS with Trehalose |
| Reconstitution | Dissolve in sterile PBS to 0.1-0.5 mg/mL or user preferred stock concentration. |
| Shipping or Handling Information | Shipped at ambient temperature |
| CoA | Batch-specific test results will be provided with the product |
| Stability | Lyophilized: Stable for 12 months at -80°C; Reconstituted: Stable for 2 weeks at 4°C, or 3-6 months at -20°C |
| Disclaimer | All of TME Scientific cell biology products are for research use ONLY and NOT for therapeutic/diagnostic applications. TME Scientific is not liable for any repercussions arising from the use of its cell biology product(s) in therapeutic/diagnostic or any other non-RUO application(s). |
