Recombinant Cytokines and Growth Factors
Cytokines are a broad category of small proteins that are crucial for cell signaling in the immune system. They are produced by various cells and help regulate the immune response by acting as messengers between cells. Cytokines influence the behavior of other cells by binding to specific receptors on their surfaces, thereby impacting processes like inflammation, immune response, cell growth, and repair.
What We Offer:
Interleukins: involved in cell communication and can affect the growth and differentiation of immune cells.
Tumor Necrosis Factors (TNFs): involved in inflammation and can induce cell death.
Interferons: play a role in antiviral defense and modulation of the immune response.
Chemokines: guide the migration of immune cells to sites of infection or injury.
Colony-Stimulating Factors (CSFs): stimulate the production and differentiation of blood cells in the bone marrow. CSFs play a crucial role in regulating white blood cell (WBC) formation and immune responses.
Growth factors: regulate cell proliferation, differentiation, survival, and tissue repair. They are essential in wound healing, angiogenesis (blood vessel formation), and immune responses.
Why TME Scientific?
Our recombinant human cytokine products are purified from the culture supernatant of HEK293 or CHO cells engineered to express specific genes encoding the target proteins. This advanced expression system ensures the production of a fully matured cytokine with proper post-translational modifications, closely resembling its natural form in vivo for optimal biological activity
TME Scientific's cytokine product offers several key benefits that make it an essential choice for researchers and clinicians:
High Purity and Quality: TME Scientific ensures that its cytokine products are of the highest purity, providing reliable results for research and clinical applications.
Consistency: Their cytokines are carefully produced to maintain consistent bioactivity and efficacy, critical for reproducibility in experiments and clinical trials.
Broad Application Range: These products are suitable for a variety of research areas, including immunology, cancer research, inflammation, and more, supporting a wide range of studies and therapeutic developments.
Proven Reliability: TME Scientific’s cytokines are backed by scientific validation and extensive testing, ensuring that their performance meets the highest standards in the field.
Customization: They offer tailored solutions for specific research needs, providing cytokines in various formulations and concentrations to suit different experimental setups.
Expert Support: TME Scientific provides exceptional customer support, offering expert guidance on product usage, applications, and troubleshooting to help maximize research success.
Choosing TME Scientific's cytokine products ensures you are using reliable, high-quality reagents to advance your scientific research and clinical endeavors.
Benefits of Supernatant Purification
Simpler Purification: No cell lysis needed, resulting in fewer contaminants and more efficient purification.
Higher Protein Quality: Secreted cytokines are more likely to be properly folded and modified, enhancing biological activity.
Improved Yields: Soluble cytokines in supernatants avoid inclusion body formation, leading to better functional yields.
Lower Endotoxin Risk: Eukaryotic systems like CHO or HEK293 cells reduce endotoxin contamination, crucial for therapeutic applications.
Easier Scalability: Supernatant purification is simpler to scale compared to intracellular methods.
Cost-Effective: Fewer purification steps and reduced need for lysis reagents lower overall costs.
Predictive Models
Models designed by TME are underpinned by extensive and reliable validation data, ensuring their accuracy and robustness and supported by a substantial body of scientific literature
Customer Focused
Customized solutions meticulously designed to address your unique needs and requirements. Striving to deliver exceptional results and a tailored experience that exceeds your expectations.
Scientific Excellence
Deep and comprehensive expertise in preclinical science and model development deliver advanced and precise scientific solutions and cutting-edge models that drive progress in the field.
Trusted collaborator
Through enduring partnerships with leading pharmaceutical companies, collaborate closely on the development of innovative and groundbreaking models designed for next-generation drugs.
Have Questions?
info@tmescientific.com
(866) 686-5707