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Human Peripheral Blood NK Cells

$799.00

Natural killer (NK) cells, one of the two subdivisions of large granular lymphocytes (LGL), have the same purpose as cytotoxic T cells: destroying pathogen-infected cells and tumours.  They differ from cytotoxic T cells in that they do not require antigen presentation to destroy infected cells, making them a part of the innate--not adaptive--immune system.  Instead, they can detect merely stressed cells, quickly initiating an immune response.  NK cells (CD56+, CD3-) are useful for research in cancer and HIV therapies.

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Natural killer (NK) cells, one of the two subdivisions of large granular lymphocytes (LGL), have the same purpose as cytotoxic T cells: destroying pathogen-infected cells and tumours.  They differ from cytotoxic T cells in that they do not require antigen presentation to destroy infected cells, making them a part of the innate--not adaptive--immune system.  Instead, they can detect merely stressed cells, quickly initiating an immune response.  NK cells (CD56+, CD3-) are useful for research in cancer and HIV therapies.

Natural killer (NK) cells, one of the two subdivisions of large granular lymphocytes (LGL), have the same purpose as cytotoxic T cells: destroying pathogen-infected cells and tumours.  They differ from cytotoxic T cells in that they do not require antigen presentation to destroy infected cells, making them a part of the innate--not adaptive--immune system.  Instead, they can detect merely stressed cells, quickly initiating an immune response.  NK cells (CD56+, CD3-) are useful for research in cancer and HIV therapies.

Description

Natural killer (NK) cells, one of the two subdivisions of large granular lymphocytes (LGL), have the same purpose as cytotoxic T cells: destroying pathogen-infected cells and tumours. They differ from cytotoxic T cells in that they do not require antigen presentation to destroy infected cells, making them a part of the innate--not adaptive--immune system. Instead, they can detect merely stressed cells, quickly initiating an immune response. NK cells (CD56+, CD3-) are useful for research in cancer and HIV therapies.

As a one-stop biomodeling service provider, TME offers NK-cell-based in vitro model systems:

  1. To study the in vitro primary human NK cell cytotoxic activity
  2. To test drug effects on the cancer-killing ability of treated & expanded NK cells – for possible clinical use of these treatments in NK cell adoptive transfer
  3. To examine the effects of continuous and intermittent cytokine exposure on NK cells
  4. To monitor natural killer cell effector functions against breast cancer cells

NK cells were isolated using negative immunomagnetic separation techniques and Institutional Review Board (IRB)-approved protocols and consent forms were used to acquire cells.

Specifications
Cat. No. CPB0014
Category Primary Cells
Tissue Peripheral Blood
Growth Properties Suspension, Round
Applications/Intended Use Research Use Only: This product is intended for laboratory research use only. It is not intended for any animal or human therapeutic use, any human or animal consumption, or any diagnostic use.
Volume/Unit 1 mL
Product Format Frozen
BioSafety II
Shipping or Handling Information Ship with dry ice
CoA Batch-specific test results will be provided with the product
Growth Conditions
  • IMDM + 10% FBS, or
  • DMEM w/ 4500mg/L D-Glucose + 10% FBS, or
  • RPMI 1640 Medium + 10% FBS
    		•
    Cryopreservation Cryopreservation Medium (Cat. No. CT002)
    Disclaimer All of TME Scientific cell biology products are for research use ONLY and NOT for therapeutic/diagnostic applications. TME Scientific is not liable for any repercussions arising from the use of its cell biology product(s) in therapeutic/diagnostic or any other non-RUO application(s).